Advances in Clinical Chemistry, Volume 63 by Gregory S. Makowski

By Gregory S. Makowski

Quantity sixty three within the across the world acclaimed Advances in medical Chemistry comprises chapters authored by way of international well known scientific laboratory scientists, physicians and study scientists. The serial offers the most recent and most recent applied sciences with regards to the sphere of scientific Chemistry and is the benchmark for novel analytical methods within the medical laboratory.

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This finding was supported 36 Marijn M. Speeckaert et al. by precipitation experiments of VLDL and LDL, which showed a partial coprecipitation of DBP, VLDL, and LDL particles. This suggests a partial presence of DBP as an LDL- and VLDL-bound plasma protein. In a similar way, serum DBP concentration correlated with serum a-tocopherol concentration. Decreased vitamin E levels and a disturbed fat malabsorption are observed in cystic fibrosis. Serum a-tocopherol strongly correlated with total lipids and serum b-lipoprotein concentrations, as it is mainly transported through VLDL and LDL particles [175].

J. 274 (Pt. 1) (1991) 237–241. D. F. A. G. Haddad, Vitamin D binding protein sequesters monomeric actin in the circulation of the rat, J. Clin. Invest. 79 (5) (1987) 1365–1370, Erratum in J. Clin. Invest. 80 (1) (1987) 277. G. Z. A. Kowalski, C. Laramore, K. Ray, P. , Identification of the sterol- and actin-binding domains of plasma vitamin D binding protein (Gc-globulin), Biochemistry 31 (31) (1992) 7174–7181. M. Sanger, G. Dabiri, B. A. G. W. Sanger, Disruption of microfilament organization in living nonmuscle cells by microinjection of plasma vitamin D-binding protein or DNase I, Proc.

Isocyanate-induced occupational asthma is the most frequent cause of occupational asthma worldwide. Proteomic analysis with bronchoalveolar lavage fluid showed an upregulation of DBP expression in patients with diphenyl-methane diisocyanate occupational asthma [159]. Serum DBP level may be used as a useful serological marker for the detection of isocyanate-occupational asthma among workers exposed to isocyanate and for prediction of the severity of airway hyperresponsiveness, with a sensitivity of 69% and specificity of 81% [160].

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